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Re: Information on Transplants from Fred Hutchinson Cancer Resear…

From: Marla

Date: 11/21/2003

Time: 6:08:22 PM

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Is this the whole article? They mentioned that 45 patients were in a study with conditions such as 1)acute leukemia, 2) chronic leukemia, 3) multiple myeloma, and 4) non-Hodgkin’s lymphoma. Then they say that survival of those with chronic leukemia was about 66%. So, what happened to the other patients with acute leukemia, multiple myeloma, and non-Hodgkin’s? And what number or percentage of those original 45 patients had chronic leukemia? Without that information, we don’t know what 66% they’re referring to. I suppose if you divide 45 by 4 (for the 4 different conditions) then you get about 11. So, 66% would be 7 people survived out of 11. (That’s assuming the patients were evenly divided). The study was only over a period of about one year, and we don’t know anything else about their condition–do they have any GVHD, endocrine dysfunction, cataracts, osteoporosis, or still on meds, etc. Also, people with *chronic* leukemia live with their conditions for quite a while. I wonder what improvement from before treatment with after treatment. Maybe they would have still been alive (surviving) a year later anyway. No mention of CBC status or the severity of their condition before transplant or how much of that one year was in hospital, etc. Makes it kind of hard to judge whether that 66% means anything. They mention that this mini-transplant is more *tolerable,* it would be more helpful if they had included an explanation of what part is more tolerable (for the benefit of the patient trying to make a decision).

Just thinking out loud here, maybe someone can interpret that article more clearly for those out there who are still trying to decide on the BMT. I’m not currently pressured to make that decision and yet still find this article mystifying, how much more would it be for a person trying to make decisions while in distress. Gee, maybe that article is not even meant to be used to help decide upon doing a mini, but that they are just continuing with research?


Last changed: September 24, 2006