Aplastic Central Active Forum
Re: elevated LDH
Date: 26 May 2004
Time: 09:47:50 -0400
Remote Name: 126.96.36.199
Pre SAA, John had a physical in July 2001. When he got his blood work, the only thing that stood out was his HDL and LDL levels. All previous blood results show a total cholesterol of 191 and a good ratio of LDL to HDL. And then in 2001, the LDL and HDL swapped places. The total remained the same. When he asked his PA, she said that his counts were good and in the normal range! So we never got a good answer from anyone on this little change in body chemistry which I believe was an indication that something was going on even though those levels were within a "normal range". Needless to say over the next nine months his counts were declining and we did not know it. In hindsight, we should have pressed them to retest his blood to see if the LDL/HDL was really off or maybe just a mistake. They assume that anyone in their 50's should expect to have high cholesterol levels! However, it still would not have changed the fact that he had SAA…but we could have found out about the SAA earlier and would have had more of an opportunity to turn it around naturally. Instead, we found out about like most when his counts were pretty much rock bottom. John's CBC at that time was border line anemic. Which was consistant with all his previous CBCs also. So no one thought there was a problem. I will never take "your too young for that to happen" or " those counts must be normal for you" anymore.
Once he was diagnosed, we pointed this out to both of his hematologist and neither felt it had anything to do with his AA. So it remains a mystery to us. We have not had any lipid panels done on him since so I don't know what they are.
I think John has always had some level of AA for long time. He's always been borderline anemic, he's been pegged as a "bleeder" and there have been times when he's been somewhat pale for years. But then no one will confirm that either.
Marla posted, awhile back some info on cholesterol that I'll look for. I think it addresses the role of LDL.
I know this doesn't help or provide you with any insights but I thought I'd share this with you since you asked.