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Re: Procrit/Aranesp

Off the Cyclosporine

From: LauraJaros@hotmail.com
Date: 17 Apr 2004
Time: 13:15:53 -0400
Remote Name:


Larry is officially off of the cyclosporine as of Thursday. The blood level was only 73 so since the doctor did not feel it was what was making his counts come up, he decided Larry should stop taking it. He is still taking a generic of Halotestin (male hormones) which is what the doctor says is bringing his numbers up. I was a bit panicked at first so the Doc had Larry come in Thursday morning for a CBC to make sure the counts are not falling with the low cylco. level. They are still moving up..White count was up to 2.5, Hgb over 10 and platelets at 39,000. What a relief.
Take care,

From: Marlene
Date: 09 Apr 2004
Time: 17:02:25 -0400
Remote Name:


I don't know answer to that one. I know that there are more things that trigger the body to produce WBC like cytokines and it's a very intricate dance that goes on. With red cells, it is a reaction to lack of oxygen, hypoxia, for people with anemia. The Hypoxia stimulates the kidneys to produce more EPO which in turn speeds up the production of red cells. From what I understand, EPO works on the immature red cells and gets them out into your blood quicker. So you have to have enough stem cells going down the red cell path in order to see an impact from the EPO. EOP doesn't act directly on the stem cells to differentiate them like the nupogen does. There's also a protein or hormone called Thombopotien produced by the liver and it's needed to stimulate both platelets and red cells. I've come to believe that your body knows how to prioritize what it needs and balances it out. So you make enough white to keep you out of danger, your platelets come up slowly cuz you can get by with so few and then the reds become the priority. Again, just my own crazy rationale. I'll have to look into this a bit more and if I come across anything, I will share it. If Marla's around, she has some great resouces that may explain it.
Anybody else with knowledge on this? It's a good question.

Last changed: 04/18/04